• LustyArgonian
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    23 months ago

    There’s actually theoretically an endothermic reaction we do. E coli can undergo an endothermic reaction if it has enough zinc. It’s entirely possible this is why we have an appendix. I’ll link studies if anyone is interested

      • LustyArgonian
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        3 months ago

        Sure. Please note that an official metastudy proving this has not come out, so you’ll have to do some dot connecting yourself.

        “Thermodynamic Studies of the Mechanism of Metal Binding to the Escherichia coli Zinc Transporter YiiP” https://www.sciencedirect.com/science/article/pii/S0021925819755392

        As shown in Fig. 2A, Zn2+ titrations began with an exothermic heat reaction, which was followed by a late endothermic reaction. This characteristic exothermic-to-endothermic transition suggests the presence of at least two sets of independent Zn2+ binding sites, accounting for the exothermic and endothermic heat reactions, respectively.

        “Association of Appendicitis Incidence With Warmer Weather Independent of Season” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530968/

        Findings of this study suggest that the incidence of appendicitis increases when the temperature increases, independent of season.

        “Association of the Bacteria of the Vermiform Appendix and the Peritoneal Cavity with Complicated Acute Appendicitis in Children” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252422/#:~:text=Bacteria identified in the lumen,in uncomplicated and complicated appendicitis.&text=Escherichia coli %2B Streptococcus spp.&text=Escherichia coli %2B Streptococcus spp

        Escherichia coli was the most commonly identified microorganism in the appendiceal lumen (83.4%; 34.7% as a single entity)

        E. coli was found in 76.2% of the cultures of the appendiceal lumen in patients with uncomplicated appendicitis (35.7% as the only pathogen) followed by P. aeruginosa (21.5%) and K. pneumoniae (14.3%) (Table 3).

        E. coli was also the predominant microorganism in complicated appendicitis (96.4%; 63.1% of them in combination with other bacteria).

        “Metabolic analysis of acute appendicitis by using system biology approach” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347980/

        As it is appeared in the table 2, concentration alteration of other metal ions such as sodium, zinc, and potassium are related to appendicitis

        “Zinc intake ameliorates intestinal morphology and oxidative stress of broiler chickens under heat stress” https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1308907/full

        Our findings indicated that dietary Zn supplementation significantly increased the feed-to-weight ratio of broilers during the experimental period under heat stress.

        Basically, not only should we all be supplementing with zinc during hotter months, but also this has indications for the purpose of the appendix and possibly a way to make air conditioning out of our feces.